Introducing PBSERUM — Professional bioremodeling enzymes, now available

pbserum HYAL Total Balance vial, front viewpbserum HYAL Balance
pbserum HYAL Total Balance box and product information
pbserum HYAL Total Balance three-vial pack
pbserum HYAL Total Balance vials with label detail
pbserum HYAL Total Balance kit overview
Recombinant EnzymeTopical ApplicationIntensive Protocol

HYAL Balance

pbserum HYAL Total Balance

High-concentration topical hyaluronidase for visible texture issues. Designed for intensive protocols that need to unify uneven skin quickly.

High-concentration hyaluronidase formula engineered for more pronounced texture concerns and intensive cosmetic protocols. Total Balance delivers a significantly higher dose of Hyaluronidase PB3000, providing more aggressive HA modulation for visible texture irregularities, localized imperfections, and cases requiring intensive correction. Designed for experienced practitioners working with patients who present more advanced texture issues — unevenness from HA accumulation, visible bumps or ridges, and skin quality concerns where the standard Precision Balance concentration is insufficient. Helps unify skin appearance, reduce visual unevenness, and restore a balanced, smooth complexion. The intensive concentration makes it suitable for targeted treatment of specific problem areas rather than broad-area application. Best used as part of a structured protocol with 2-4 sessions spaced 21 days apart, allowing the tissue to respond and remodel between treatments.

Pack: 3 powder vials

EnzymeHyaluronidase PB3000
TargetsHyaluronic acid
MethodTopical

1–4 units

5–9 units

10–19 units

20–30 units

31–40 units

41+ units

$225.00

Current

$213.75

Save 5%

$202.50

Save 10%

$180.00

Save 20%

$157.50

Save 30%

$135.00

Save 40%

Prices in US$. Volume pricing is based on the total quantity across your entire cart.

1

SKU: PBS-HYB-TOT·USD

All prices exclude tax.

pbserum HYAL Balance

Next-generation topical solution with hyaluronidase in different concentrations, formulated to visibly improve uneven skin texture and promote a more harmonious appearance.

ResetTopicalProfessional

How It Works

Recombinant enzyme technology — precision molecular biology for skin renewal

Hyaluronidase molecular structure

Hyaluronidase

PB3000

Targets: Hyaluronic acid

Breaks down excess or previously injected hyaluronic acid, a specific GAG that holds 1000x its weight in water.

Learn more about Hyaluronidase

Mechanism of Action

Enzyme Action

Precision-engineered enzymes target and break down damaged tissue components in the extracellular matrix.

Cellular Response

The cleared environment signals fibroblasts to activate, initiating collagen and elastin synthesis.

Tissue Renewal

New collagen and elastin fibers organize into a healthy, structured matrix with improved firmness and texture.

Bioremodeling Cascade

A three-phase protocol for complete skin restoration

This Product

Phase 1

Reset

Enzymes clear damaged, fragmented tissue — collagen debris, excess HA, fat deposits, matrix congestion. Creates a clean biological canvas.

Reveal, Plus, Hyal balance

Phase 2

Stimulation

The cleared environment responds optimally to active ingredients — growth factors, peptides, vitamins, antioxidants reach fibroblasts directly.

Specific, Veluria

Phase 3

Maintain

Home care supports regeneration with keratinase-enhanced penetration. New collagen and elastin fibers organize into healthy tissue.

Smartker

Treatment Protocol

Professional application guide

2-4 sessions, spaced 21 days apart, 20 minutes each.

Application Steps

  1. 1.

    Cleanse treatment area thoroughly

  2. 2.

    Assess HA distribution and texture irregularities

  3. 3.

    Reconstitute high-concentration hyaluronidase solution

  4. 4.

    Apply to targeted areas with controlled technique

  5. 5.

    Monitor for immediate response

  6. 6.

    Apply hydrating post-treatment product

What to Expect

Visible improvement typically begins after the first session and progresses with each treatment. The enzymatic bioremodeling cascade continues working between sessions — the 21-day interval allows the tissue to complete its natural regeneration cycle before the next application.

Indicated for: Texture issues, Intensive protocols

Coming soon
How to apply

Composition

INCI
  • Mannitol
  • Disodium EDTA
  • Hyaluronidase
Recombinant enzymePer PBSerum qualitative & quantitative composition.

What's in the Box

Hyaluronidase Powder Vials

High-concentration lyophilized hyaluronidase for intensive texture correction

3x

7 3/16 × 1 5/8 × 2 1/8 in • 0.06 lb

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