Introducing PBSERUM — Professional bioremodeling enzymes, now available
pbserum Plus



Plus
pbserum Plus Drain+
Hyaluronidase enzyme for drainage, cellulite, and sagging. Central triad component — recommended across most Plus indications for synergistic effect.
Recombinant Hyaluronidase PB3000 in a lyophilized format for customizable cocktail mixing. Drain+ breaks down excess hyaluronic acid — a glycosaminoglycan that holds up to 1000× its weight in water — to reduce fluid retention, improve tissue drainage, and create a smoother, more balanced skin appearance. Always recommended as part of the enzyme triad for synergistic effect. When combined with Slim+ and Smooth+, Drain+ creates the drainage pathway that amplifies the action of the other enzymes. Hyaluronidase clears the water-retaining HA matrix, allowing lipase and collagenase better access to their respective targets. The 10-vial format enables practitioners to build multiple cocktail combinations across a treatment course, adjusting ratios as tissue responds. Particularly effective for cellulite-related fluid retention, post-procedure swelling management, and sagging skin where excess tissue hydration contributes to volume loss. Each vial contains 0.08g of lyophilized enzyme powder.
Pack: 10 powder vials (0.08g each)
Prices in US$. Volume pricing is based on the total quantity across your entire cart.
SKU: PBS-PLS-DRN·USD
All prices exclude tax.
pbserum Plus
Personalized recombinant enzyme solutions to achieve precise results. Three enzymes (Slim+, Drain+, Smooth+) mixed in custom ratios per indication. Effective, safe and versatile enzyme cocktail for facial and body treatments.
Also in this line
How It Works
Recombinant enzyme technology — precision molecular biology for skin renewal

Hyaluronidase
PB3000Targets: Hyaluronic acid
Breaks down excess or previously injected hyaluronic acid, a specific GAG that holds 1000x its weight in water.
Learn more about Hyaluronidase →Mechanism of Action
Enzyme Action
Precision-engineered enzymes target and break down damaged tissue components in the extracellular matrix.
Cellular Response
The cleared environment signals fibroblasts to activate, initiating collagen and elastin synthesis.
Tissue Renewal
New collagen and elastin fibers organize into a healthy, structured matrix with improved firmness and texture.
Bioremodeling Cascade
A three-phase protocol for complete skin restoration
Phase 1
Reset
Enzymes clear damaged, fragmented tissue — collagen debris, excess HA, fat deposits, matrix congestion. Creates a clean biological canvas.
Reveal, Plus, Hyal balance
Phase 2
Stimulation
The cleared environment responds optimally to active ingredients — growth factors, peptides, vitamins, antioxidants reach fibroblasts directly.
Specific, Veluria
Phase 3
Maintain
Home care supports regeneration with keratinase-enhanced penetration. New collagen and elastin fibers organize into healthy tissue.
Smartker
Treatment Protocol
Professional application guide
4-8 sessions, spaced 14 days apart, 45 minutes each.
Application Steps
- 1.
Cleanse treatment area thoroughly
- 2.
Select enzyme vials based on treatment indication
- 3.
Reconstitute and mix custom cocktail ratio per protocol
- 4.
Apply topically with targeted massage technique
- 5.
Leave on skin for recommended duration
What to Expect
Visible improvement typically begins after the first session and progresses with each treatment. The enzymatic bioremodeling cascade continues working between sessions — the 14-day interval allows the tissue to complete its natural regeneration cycle before the next application.
Indicated for: Face, Body, Drainage, Cellulite, Sagging
Mixing Ratios
| Indication | Recipe |
|---|---|
| Body contouring | 2x Slim+ : 1x Drain+ |
| Cellulite and drainage | 1x Slim+ : 2x Drain+ |
| Surface irregularities | 2x Smooth+ : 1x Drain+ |
Composition
INCI- Mannitol
- Sodium Phosphate
- Disodium EDTA
- Hyaluronidase
What's in the Box
Enzyme Powder Vials
Lyophilized Hyaluronidase PB3000 — 0.08g per vial
10x5 5/16 × 2 1/4 × 2 15/16 in • 0.34 lb
Complementary Products
Build a complete treatment protocol


