Introducing PBSERUM — Professional bioremodeling enzymes, now available
pbserum Plus



Plus
pbserum Plus Slim+
Lipase enzyme targeting localized fat, double chin, and body contouring. Part of the customizable Plus triad — mix with Drain+ and Smooth+ per indication.
Recombinant Lipase PB500 in a lyophilized format for customizable cocktail mixing. Each case contains 10 powder vials, enabling practitioners to create personalized enzyme cocktails tailored to each patient's specific indications. Lipase catalyzes the breakdown of triglycerides in fat cells, reducing adipose volume for visible body contouring results. The Plus line's power lies in synergy: clinical experience demonstrates significantly enhanced results when Slim+ is combined with Drain+ (hyaluronidase for drainage) and Smooth+ (collagenase for tissue remodeling) in custom ratios. The total cocktail volume per procedure is 7.5ml, with the practitioner adjusting the ratio of each enzyme based on the treatment area and desired outcome. Typical cocktail ratios: Body contouring (2× Slim+ : 1× Drain+), Submental area (1× Slim+ : 1× Drain+), Cellulite with fibrosis (1× Slim+ : 1× Smooth+ : 1× Drain+). Each vial contains 0.07g of lyophilized enzyme powder for reconstitution.
Pack: 10 powder vials (0.07g each)
Prices in US$. Volume pricing is based on the total quantity across your entire cart.
SKU: PBS-PLS-SLM·USD
All prices exclude tax.
pbserum Plus
Personalized recombinant enzyme solutions to achieve precise results. Three enzymes (Slim+, Drain+, Smooth+) mixed in custom ratios per indication. Effective, safe and versatile enzyme cocktail for facial and body treatments.
Also in this line
How It Works
Recombinant enzyme technology — precision molecular biology for skin renewal

Lipase
PB500Targets: Triglycerides in fat cells
Breaks down triglycerides stored in adipocytes, reducing fat cell volume without hormonal dependence. Works synergistically with lyase which clears ECM to expose more fat cells.
Learn more about Lipase →Mechanism of Action
Enzyme Action
Precision-engineered enzymes target and break down damaged tissue components in the extracellular matrix.
Cellular Response
The cleared environment signals fibroblasts to activate, initiating collagen and elastin synthesis.
Tissue Renewal
New collagen and elastin fibers organize into a healthy, structured matrix with improved firmness and texture.
Bioremodeling Cascade
A three-phase protocol for complete skin restoration
Phase 1
Reset
Enzymes clear damaged, fragmented tissue — collagen debris, excess HA, fat deposits, matrix congestion. Creates a clean biological canvas.
Reveal, Plus, Hyal balance
Phase 2
Stimulation
The cleared environment responds optimally to active ingredients — growth factors, peptides, vitamins, antioxidants reach fibroblasts directly.
Specific, Veluria
Phase 3
Maintain
Home care supports regeneration with keratinase-enhanced penetration. New collagen and elastin fibers organize into healthy tissue.
Smartker
Treatment Protocol
Professional application guide
4-8 sessions, spaced 14 days apart, 45 minutes each.
Application Steps
- 1.
Cleanse treatment area thoroughly
- 2.
Select enzyme vials based on treatment indication
- 3.
Reconstitute and mix custom cocktail ratio per protocol
- 4.
Apply topically with targeted massage technique
- 5.
Leave on skin for recommended duration
What to Expect
Visible improvement typically begins after the first session and progresses with each treatment. The enzymatic bioremodeling cascade continues working between sessions — the 14-day interval allows the tissue to complete its natural regeneration cycle before the next application.
Indicated for: Face, Body, Submental, Localized fat, Double chin, Body contouring
Mixing Ratios
| Indication | Recipe |
|---|---|
| Body contouring | 2x Slim+ : 1x Drain+ |
| Submental area | 1x Slim+ : 1x Drain+ |
| Surface irregularities | 2x Smooth+ : 1x Drain+ |
Composition
INCI- Mannitol
- Sodium Phosphate
- Lipase
- Disodium EDTA
What's in the Box
Enzyme Powder Vials
Lyophilized Lipase PB500 — 0.07g per vial
10x5 5/16 × 2 1/4 × 2 15/16 in • 0.36 lb
Complementary Products
Build a complete treatment protocol


